Viral Therapy of Cancer
HarringtonThis book provides a comprehensive yet succinct overview of the current status of viral therapy of cancer. Chapters coherently present the advances made with individual agents and review the biological and clinical background to a range of viral therapies: structured to proceed from basic science at the bench to the patient’s bedside, they give an up-to-date and realistic evaluation of a therapy’s potential utility for the cancer patient.
- Presents state of the art knowledge on how viruses can be, and have been, used in novel therapeutic approaches for the treatment of cancer
- Describes the use of viruses as oncolytic agents, killing cells directly
- Editors are experts in the field, with experience of both laboratory and clinical research
Viral Therapy of Cancer is essential reading for both basic scientists and clinicians with an interest in viral therapy and gene therapy.Content:
Chapter 1 Adenoviruses (pages 1–17): Kate Relph, Kevin J. Harrington, Alan Melcher and Hardev S. Pandha
Chapter 2 Application of HSV?1 Vectors to the Treatment of Cancer (pages 19–53): Paola Grandi, Kiflai Bein, Costas G. Hadjipanayis, Darren Wolfe, Xandra O. Breakefield and Joseph C. Glorioso
Chapter 3 Adeno?Associated Virus (pages 55–68): Selvarangan Ponnazhagan
Chapter 4 Retroviruses (pages 69–81): Simon Chowdhury and Yasuhiro Ikeda
Chapter 5 Lentiviral Vectors for Cancer Gene Therapy (pages 83–94): Antonia Follenzi and Elisa Vigna
Chapter 6 Poxviruses as Immunomodulatory Cancer Therapeutics (pages 95–114): Kevin J. Harrington, Harde